Key findings: Prescribing trends Using a subset of Truveta Data, Truveta Research identified people who were prescribed a GLP-1 RA between January 01, 2018 and March 31, 2025
Some patients report less nausea when injecting during eating windows, while others tolerate injection fine during fasts
Each test result is documented in a Certificate of Analysis (COA), which you can download directly from each product page or from our centralized COA library
: GLP-1 ( ), GLP-1RAs( ), ( )
Side Effects Profile All three medications share common side effects, primarily gastrointestinal: Nausea (usually temporary, worst in first few weeks) Diarrhea or constipation Abdominal discomfort Reduced appetite (this is the goal, but can feel uncomfortable initially) The higher dose of Wegovy may cause more pronounced side effects initially, while Saxendas daily dosing can offer more stable blood levels with potentially fewer ups and downs
But medications like Ozempic, Wegovy, and Mounjaro only started making waves about a decade ago