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However, bioavailability through nasal delivery is lower than injection

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For most cytokines tested, no differences were observed between control groups receiving different diets

Critically, this redox adaptation is a key mechanism of resistance to radiotherapy and many chemotherapeutic agents, such as cisplatin and doxorubicin, which depend on generating oxidative damage to exert their cytotoxic effects [33]

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Nava A, Thiene G, Canciani B, et al