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Tirzepatide (Mounjaro) begins affecting your body right after you receive your shot

Avoid exercising immediately after meals, though, as this can disrupt digestion

Key Takeaways Retatrutide is a triple GLP-1/GIP/glucagon receptor agonist

The heaviest shedding phase, usually coinciding with the highest rate of weight loss

Phase 2 data showed similar overall tolerability but the GI signals are worth watching in Phase 3

We will also continue to advocate for a system that better aligns with the science. In a clinical study, tirzepatide 5 mg, along with a reduced calorie diet and increased physical activity, achieved an average of 15% weight loss over 72 weeks compared to 3.1% for placebo