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Side effects observed in Phase 2 studies include nausea, vomiting, diarrhoea, decreased appetite, and injection-site reactions

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This review uniquely juxtaposes these disorders, proposing that despite discrepant etiologies, early-life nutritional imbalances whether deficiency or excess, converge on common endocrine, immunological, epigenetic and gut-microbiome-related pathways and metabolic outcomes, with intergenerational implications

AOM discontinuation was high throughout 2023 and early 2024 due to medication unavailability

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