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Pregnancy Advise women who are exposed to REPATHA during pregnancy that there is a pregnancy safety study that monitors pregnancy outcomes

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Compared to obese wild-type control animals, obese IFN- knockouts exhibit better IS, smaller adipocyte size, and lower cytokine expression [79]

They found that at the highest dosage of 4.8 mg survodutide weekly, study participants lost 14.9% of their body weight in comparison with a placebo group (2.8% weight loss) [122]