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4 Without lifestyle changes, the weight loss people see while taking GLP-1s usually doesnt last, she explains

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That type of evidence can help generate scientific theories, but it does not prove that a treatment produces meaningful real-world results in humans

The medication carries a Boxed Warning regarding thyroid C-cell tumors based on rodent studies, though the clinical relevance to humans remains uncertain

Two novel agentsEnsifentrine (11) (a phosphodiesterase inhibitor) and Dupilumab (12) (an IL-4 receptor antagonist)have recently been incorporated into the 2025 Global Initiative for Chronic Obstructive Lung Disease (GOLD) recommendations for preliminary clinical application

It is not approved for weight loss