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[DOI] [PMC free article] [PubMed] [Google Scholar] 191.Yaribeygi, H., et al., Boosting GLP-1 by natural products

As an osmotically active compound, creatine draws water into muscle cells when its absorbed, which may result in a short-term weight increase of 2.26.6 pounds (13 kg)

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We may also recommend tirzepatide for individuals with a BMI of 27 kg/m or higher if they have at least one weight-related health condition, such as high blood pressure, type 2 diabetes, or elevated cholesterol

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Attempts to remove a substance from the whole organism may have the effect of increasing the burden present in one part of the organism