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Studies have consistently shown that the weight loss associated with HCG diets is not due to the hormone itself but rather the extremely low-calorie intakeusually between 500-800 calories per day

Previously, Adler et al

May affect neurologic signaling and nerve integrity

This is why patients with neurological involvement are often maintained on a more frequent schedule (every 2 months rather than every 3 months)

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Some need 1,000 mcg if levels stay low on the lower dose