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Although without total consensus, six components have been proposed to constitute the metabolic syndrome[300]: Abdominal obesity (or increased waist circumference), atherogenic dyslipidemia (hypertriglyceridemia and low high-density lipoprotein cholesterol concentrations), raised blood pressure, insulin resistance with glucose intolerance, pro-inflammatory state (elevated C-reactive protein) and a pro-thrombotic state (with increased plasminogen activator inhibitor-1 and fibrinogen)

An ELF score of 10.51 or above indicates likely advanced fibrosis and warrants referral to a hepatologist

Approximately 10 5 cells of CO23, CO23MCFG and CO23RFLC strains were serially diluted and spotted onto YPD plates treated or not with 4 mM H 2 O 2 in absence (1) or in presence of GSH precursors 0.02 M glutamate, 0.02 M cysteine, 0.02 M, glycine (2) or with 5 mM BSO (L-buthionine-sulfoximine) (3)

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