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Symptoms of sickle cell anemia include pain (especially in the back and hips), fatigue, reduced exercise tolerance, and jaundice (Mayo Clinic 2011d

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175 Classical pathophysiological mechanisms of GLP-1 GLP-1 signaling pathway GLP-1 initiates signaling by binding to its receptor, GLP-1R, which is a G-protein-coupled receptor

The B-factor values of the selected PDB IDs were analyzed using UCSF Chimera [38], which were visualized with attribute representation in a range of 20 (in blue) to 80 2 (in red)