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Osteoarthritis is also biologically heterogeneous, involving cartilage, bone, synovium, nerves, and systemic metabolic factors rather than a single disease pathway. Mandelbaum said there are lifestyle factors people can adopt to help lower the risk of osteoarthritis as well as its painful effects

Common side effects include: Nausea Vomiting Constipation Diarrhea Bloating Acid reflux Loss of appetite Less common but important risks include: Gallstones Pancreatitis (rare) Dehydration Temporary worsening of diabetic retinopathy in selected patients with rapid glucose improvement Your endocrinologist will monitor for these risks and adjust treatment if needed

For better results try for 5 to 6 months

You would not give it to them daily

doi: 10.1056/NEJMoa1607141

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