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[38-40] Carotenoids and Vitamin A can absorb peroxyl radicals and singlet oxygen and regulate the expression of COX-2, NO, production, cell differentiation, bone metabolism, and vision

Summary of phase 2 clinical trials of GLP1R agonists for PD Ex-4: exenatide-4, mTOR: mechanistic target of rapamycin, IRS1: insulin receptor substrate 1, MDS-UPDRS: Movement Disorder Society-Sponsored Revision of the Unified Parkinsons Disease Rating Scale, PD: Parkinsons disease, PKB: protein kinase B, DAergic: dopaminergic, GLP1R: glucagon-like peptide-1 receptor.

Leiss V, Flockerzie K, Novakovic A, et al

Aspe, C.J.D

While Rascols leading hypothesis is that GLP-1 drugs are working to reduce inflammation, he acknowledges that the reductions in Parkinsons symptoms in his study could also be explained by something else

Serotonin metabolism is dysregulated in cholangiocarcinoma, which has implications for tumor growth