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This mechanism becomes clinically important when using high-dose oral supplements (typically 1000 micrograms or more), as it can provide adequate absorption even when the intrinsic factor pathway is impaired

The vitamins may take some time to fully absorb into the body, meaning with injections it may take a few days or weeks before the effects are noticeable, and may take a bit longer for vitamin supplements, but at the recommendation of a doctor, you should feel better with the correct amount of vitamin B12 being taken regularly

This is especially true for people who were low on B12 to begin with

That single fact drives everything about how its administered

We strongly advise against this unless your research protocol specifically calls for it and youve verified their chemical compatibility

This technique decreases pain to the patient, BUT most importantly it prevents the instilled solution from seeping into the subcutaneous tissue