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Unlike corticosteroids or broad immunosuppressants, KPV does not appear to suppress immune function globally its NF-kB inhibition is targeted and does not eliminate the immune response, only attenuates the pro-inflammatory cascade

For example, Zinc finger TF, pilin-like TF, and HMG-box TF were increased by 0.7-, 0.3-, and 0.2-fold, while the MEIS1 and heat shock TFs were decreased by 1.1- and 0.7-fold induced by MT treatment, respectively

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(Oxf.) 64 , 444449 (2006)

The most quantitatively striking effect reported in the Dihexa literature is on dendritic spine density in rat hippocampal neuron cultures