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An interim meta-analysis was planned when at least 100 participants had experienced one component of MACE-4

In the OASIS 4 trial, adults taking the Wegovy pill at 25 mg lost an average of 13.6% of their body weight over 64 weeks, compared with 2.2% on placebo

Neurosci Biobehav Rev 169:105995

Spector AC, Travers SP

(4) The researchers investigated cell culture models of fibrosis, which also expressed senescence markers such as more -galpositive cells and higher p16 and p21