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In subsequent papers, we will explore AI-enabled drug discovery in more depth as an emerging and increasingly investable theme examining the key catalysts and evidence base that could translate scientific progress into durable value creation

Target System

Byon CH, Javed A, Dai Q, Kappes JC, Clemens TL, Darley-Usmar VM et al (2008) Oxidative stress induces vascular calcification through modulation of the osteogenic transcription factor Runx2 by AKT signaling

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453 Interestingly, Nrf1 is downregulated in PD, suggesting that Nrf1 upregulation may alleviate impaired protein turnover, thereby reducing proteotoxicity and enhancing neuronal resilience against PD pathogenesis

10.1016/0006-2952(92)90207-Y Biochem