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Types of Diuretics: 1 Loop Diuretics (e.g., Furosemide, Bumetanide) Act on the Loop of Henle Potent diuresis Commonly used in acute heart failure and edema 2 Thiazide Diuretics (e.g., Hydrochlorothiazide, Chlorthalidone) Act on the distal convoluted tubule Mild to moderate diuresis Often used for hypertension 3 Potassium-Sparing Diuretics (e.g., Spironolactone, Amiloride) Act on the collecting duct Minimize potassium loss Used in heart failure and hypertension 4 Carbonic Anhydrase Inhibitors (e.g., Acetazolamide) Act on the proximal convoluted tubule Mild diuresis Indicated in glaucoma, epilepsy, and altitude sickness 5 Osmotic Diuretics (e.g., Mannitol) Increase osmotic pressure in renal tubules Used in cerebral edema and acute kidney injury Clinical Applications: Hypertension management Edema treatment in heart failure, liver, and kidney disease Management of hypercalcemia and hyperkalemia Bottom line: Diuretics are powerful medications that support fluid balance and renal function, each class tailored to specific clinical needs

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