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Those who are pregnant, breastfeeding, or about to be pregnant do not meet eligibility for this therapy

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Mandelbaum: There are risks, some of which we dont know, like tumor risk, for example

Epub 2014/09/23

Plerixafor acts by reversibly blocking the binding between chemokine CXC-receptor 4 (CXCR4) and the stromal cell derived factor-1 triggering the mobilization of progenitor cells into the peripheral blood

Both are aligned with standard guidelines approved by regulatory authorities