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There may be some mild discomfort and minor swelling present, (which is normal), however, persistant pain, swelling tat expands beyond the injection site, and heat could be a sign of an infection

Acetylcholine stimulates alveolar macrophages to release inflammatory cell chemotactic activity

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55 SakamotoK.YonokiY.KubotaY.KuwagataM.SaitoM.NakaharaT.et al (2006)

This drives severe oxidative stress in neural and hepatic tissue, aggressively countering the intended neuroprotective goals of a longevity protocol