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Strongly stimulates GH but with two marked off-target effects: a pronounced increase in appetite (orectic effect via stimulation of ghrelin secretion itself), and a moderate increase in cortisol and prolactin

doi:10.1007/s00404-018-4688-6 Franik S, Eltrop SM, Kremer JA, Kiesel L, Farquhar C

Glucocorticoid receptors recruit the CaMKII-BDNF-CREB pathways to mediate memory consolidation

Its also possible that because these drugs target parts of the brain that regulate appetite, they could also affect compulsive behaviors that might involve those brain regions, like using alcohol or stimulants, gambling, smoking or even nail-biting

All combination protocols require clinical oversight to manage dosing, sequencing, and monitoring

The argument is simple