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The non-metabolizable glucose analog and SGLT-1 agonist, -methylglucopyranoside, is also a potent stimulator of GLP-1 release from primary intestinal L-cell cultures, highlighting this transporter as a major stimulator of hormone release from EECs (27)

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(1987) Cyclic lactam analogues of alpha-melanotropin Journal of Medicinal Chemistry 30(11):21262130

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Early data suggest that GLP-1 receptor agonists may normalize hyperactivity in limbic regions associated with craving while enhancing prefrontal inhibitory control