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Clinical trials have demonstrated substantial weight loss in obesity studiesapproximately 15% at 5 mg, 19.5% at 10 mg, and 20.9% at 15 mg after 72 weeks of treatment

Our determination is based on our conclusions that supply meets or exceeds current demand, and that, based on our best judgment looking at the available information with its limitations, supply will also meet or exceed projected demand, the agency said in a new advisory