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Possible explanations include rapid changes in body composition, biomechanical adjustment, or dehydration

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Last Published 04.01.2026 Effective Date: 04.01.2026 This policy addresses the use of erythropoiesis-stimulating agents (ESAs), including Aranesp (darbepoetin alfa), Epogen (epoetin alfa), Mircera (methoxy polyethylene glycol-epoetin beta [MPG-epoetin beta]), Procrit (epoetin alfa), and Retacrit (epoetin alfa)

By filling the slot completely, the system allows the wires to be more completely expressed, eliminating or greatly reducing wire-bending or bracket-repositioning