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Databases searched (and their content coverage dates) were Ovid MEDLINE(R) (1946+ including epub ahead of print, in-process, and other nonindexed citations), Ovid Embase (1974+), Ovid APA PsycInfo (1967+), Ovid Cochrane Central Register of Controlled Trials (1991+), Ovid Cochrane Database of Systematic Reviews (2005+), Web of Science Core Collection via Clarivate Analytics (1975+), and Scopus via Elsevier (1974+)
Study selection criteria were defined in terms of population, interventions, comparisons, outcomes and study design (PICOS) to ensure that potentially relevant studies were selected systematically to minimise bias [20, 21]
Bates et al., 1994)
Reduced basal autophagy and impaired mitochondrial dynamics due to loss of Parkinsons disease-associated protein DJ-1
Any smaller peaks represent impurities
Strategies that support microbial diversity, including probiotic supplementation (particularly Lactobacillus and Bifidobacterium strains studied in atopic conditions), prebiotic fiber intake, and avoidance of unnecessary antibiotics, create a more favorable environment for peptide interventions
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