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Optimise general joint health through evidence-based lifestyle measures: Maintain a healthy weight to reduce mechanical stress on weight-bearing joints Engage in regular low-impact exercise such as swimming, cycling, or walking to maintain joint mobility and strengthen supporting muscles Apply heat or cold therapy as appropriateheat for stiffness, cold for acute inflammation Follow a balanced diet with plenty of fruits, vegetables, and whole grains

Johnson MD, Miocinovic S, McIntyre CC, Vitek JL

HHcy is suspected to cause neurotoxicity [75,76], and most neurological and psychiatric disorders appear to result from a combination of various genetic and environmental factors [77]

While GLP-1 drugs can result in 15-25% total body weight loss, surgery often achieves 25-35% or more, with higher rates of long-term maintenance and remission of related diseases