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These neurons may also regulate intestinal growth through crypt fission, a novel effect of GLP-1 that has recently been identified (97)

Indeed, local Ex4 infusion into the LDTg suppresses alcohol-induced locomotor stimulation, dopamine release in the NAc, memory of alcohol reward, and alcohol drinking in male rodents (Vallof et al., 2019a)

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At the same time, serum IGF-1 levels below 80 ng/ml can be detrimental, especially after the age of 75