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Beyond gastrointestinal effects, clinical data and class-level evidence from licensed incretin agents (semaglutide, tirzepatide) have flagged concerns regarding: Heart rate elevation: Increases in resting heart rate are a recognised class effect of GLP-1 receptor agonists, documented in the SmPCs for semaglutide (Wegovy) and tirzepatide (Mounjaro)

Instead, you'll follow a "step-up" dosing plan over several months

This resolves for most within days as your stomach adapts to slower emptying

When fat decreases and muscle increases, your body becomes stronger and leaner

We will analyze conceivable mechanisms, risk factors, and managing remedies

To learn how the drugs affect male fertility, Natesh and her colleagues searched the literature for randomized controlled trials of GLP-1 drugs that included measurements of testosterone levels in men