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doi:10.1016/j.ghir.2004.03.006
Anaphylactic reaction after injection of vitamin B12 Heres a case of two female patients with pernicious anemia who had adverse reactions to B12 shots (hydroxocobalamin)
Some other ways to reduce pain include trying not to tense your arm while you're being vaccinated and moving your arm after vaccination (or exercising) to increase blood flow and help disperse the vaccine throughout the area
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If you experience it, its pretty easy to treat with products you likely already have at home: Cold packs can reduce pain, swelling, and itching OTC pain medications can curb pain and inflammation In some cases, you could have itching, irritation, or redness at the injection site