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CNS disorders with widespread iron accumulation in areas, including the basal ganglia, might not fully benefit if the drug mainly targets certain areas

- Aumento de la tasa metablica y permite una produccin de energa superior

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Tissue type considerations further support synergistic combinations

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Metabolic findings in rodents have a long history of not translating cleanly, so the fat-loss story should be read as promising preclinical data, not an established human outcome