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In the sections that follow, we build on this conceptual framework to examine how major proteostasis machineries contribute to cellular and organ-level resilience and how their failure drives pathology across cardiovascular, cancer, metabolic, neurodegenerative and autoimmune disorders and highlight therapeutic strategies aimed at reinforcing proteostasis resilience

10.1210/jc.2001-012054 112 MasudaT.TsurudaY.MatsumotoY.UchidaH.NakayamaK

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The team also looked at blood vessel and valve tissue from people with heart disease who had undergone surgery for their condition

Levodopa inhibits the development of form-deprivation myopia in guinea pigs