With the high price tag on medications like Wegovy and Saxenda, the employers and health plans paying for these treatments want to know how they can optimize their investments
Percentage Body Weight Change A total of eight RCTs involving 7,179 participants were included in the network meta-analysis, evaluating the mean percentage change in body weight from baseline
most patients improve by week 2 without intervention beyond hydration and dietary adjustment
Whether the GIP contribution is mainly appetite-related, metabolism-related or a combination is still being studied, but the two molecules are mechanistically different in a way that matters for outcomes
In the absence of head-to-head comparisons, indirect evidence across heterogeneous trial populations with placebo or inferior active comparators provides limited guidance for clinical decision-making
The majority of participants did not discontinue treatment because of these side effects, speaking to their severity, she added