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In particular, low sulforaphane doses consistently exhibit beneficial effects in preclinical neuronal cell cultures models and avoid cytotoxic effects of higher sulforaphane doses

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18,20 The DEP domain not only binds to FZD but can also change its conformation and thereby dimerize, triggering the WNT/FZD signalosome

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The group N=C=S has a linear structure that was proposed as early as 1929 by Perschke [99]

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