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But until now, there hasnt been any data from large epidemiologic studies. To help fill this knowledge gap, UBC researchers examined health insurance claim records for approximately 16 million U.S

Collectively, these studies suggest that xCT is beneficial for cancer cells by suppressing ferroptosis, while glucose deprivation and NADPH depletion caused by a reduction in carbon from glucose entering the PPP can promote cancer cell death [26,48]

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