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Therefore, studies that extend the follow-up time and increase the sample size to observe the role of GLP-1 in atherosclerosis can be further developed

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Some patients report subjective improvements in energy levels and metabolic symptoms when using these medications, though such anecdotal reports cannot substitute for controlled clinical evidence

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7.2.1 Non-monotonic dose-response relationships 7.2.1.1 Mechanistic understanding of NMDR effects Many EEDs exhibit non-monotonic dose-response curves where low-dose exposure produces greater biological effects than high-dose exposure (139)