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Crystallization The KRAS G13C protein was diluted to 2 mg/mL and incubated with a 3-fold excess of the acryl-bearing nucleotide 7b in 100 mM CHES (pH 9.5), 50 mM NaCl, 1 mM EDTA, 1 mM TCEP, and 5 % glycerol at room temperature

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These long-acting, drug-fused IgGs act as excellent peptide ferries, but they are costly because the antibodies must be extracted and modified in a laboratory before they can be effective inside that same person's body

Furthermore, various classes of bacterial compounds like LPS, have been shown to penetrate systemic circulation, even reaching the CNS

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