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When fat embolism occurs via arterial routes, fat particles can inadvertently enter superficial arteries such as the angular artery, facial artery, or superficial temporal artery, eventually reaching the cerebral circulation due to hemodynamics [24]

Rather than targeting one receptor pathway with high specificity, retatrutide activates three distinct hormone receptors simultaneously: GLP-1 (glucagon-like peptide-1), GIP (glucose-dependent insulinotropic polypeptide), and glucagon

doi:10.1097/JCP.0000000000000210 105 Bloch, M

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