Who may benefit from combined HRT and GLP-1 treatment Not everyone wants or benefits from both treatments, but certain situations may make the combination worth exploring with a clinician: People in perimenopause or menopause experiencing stubborn weight changes despite consistent efforts Those already on HRT who want additional support for weight management People experiencing weight changes alongside metabolic concerns to discuss with a clinician Those who haven't responded well to GLP-1 alone and have hormonal factors at play What works for one person may not be appropriate for another
Some people report nausea, vomiting, headache, facial flushing, and post-injection redness
Who shouldnt take retatrutide
If nausea persists beyond 8 weeks at a given dose, the prescribing information supports staying at the current dose rather than escalating 1
The nausea associated with semaglutide is thought to result from both peripheral effects on gastric emptying and central effects on nausea centers in the brain
Glucagon- like peptide 1 Analogues as Adjunctive Therapy for Patients with Type 1 Diabetes: an Updated Systematic Review and Meta-analysis
