187 Extracellular HSP70 forms activation complexes with co-chaperones such as HSP90, Hop, and HSP40, enhancing breast cancer cell migration and invasion by increasing MMP2 activity
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This technique enables precise incorporation of modified residues such as Aib and D-2Nal, thereby contributing to the peptides stability and biological selectivity
Because of the nonspecific activation of lytic peptide, they discovered that, when the peptide enters the cell line, it specifically cleaves secreted metalloproteinases, breaking the peptide bond [48]
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