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Description

187 Extracellular HSP70 forms activation complexes with co-chaperones such as HSP90, Hop, and HSP40, enhancing breast cancer cell migration and invasion by increasing MMP2 activity

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Because of the nonspecific activation of lytic peptide, they discovered that, when the peptide enters the cell line, it specifically cleaves secreted metalloproteinases, breaking the peptide bond [48]

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