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For example, the second derivative of is , which is zero for but is strictly convex

doi: 10.1016/j.coi.2012.12.005

Their activation permits calcium influx and initiates intracellular signaling cascades involving calmodulin kinase II (CaMKII), cAMP Response Element Binding Protein (CREB) and MAPK, culminating in the transcription of genes required for long-lasting synaptic enhancement [208]

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[7] This decline correlates directly with increased oxidative stress markers and age-related health issues

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