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The Phase 2 trial also included a meta-analysis benchmark: a 2025 systematic review and meta-analysis of 3 RCTs involving 878 patients found a mean body weight reduction of 14.33% versus placebo, with a BMI reduction of 5.38 and waist circumference reduction of 10.51 cm

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Common side effects include: As with any supplement, its recommended to consult a healthcare provider before starting Epithalon, especially if there are any pre-existing health concerns