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The SCD patient samples (n = 24) used for this study were anonymous discard samples obtained with UCSF IRB approval from the SCD clinic at UCSF Benioff Childrens Hospital in Oakland (BCHO) that included a waiver of Informed consent for use of anonymized samples

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Nature 620 , 480 (2023)

If the medication has been refrigerated, some patients prefer to let it sit at room temperature for approximately 15-30 minutes before injection to reduce injection site discomfort, though this step is optional