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The importance of pre-use refrigeration cannot be overstated

If you experience symptoms of the following adverse effects, stop taking semaglutide and contact your healthcare provider: Thyroid tumors: Semaglutide may increase the risk for certain types of thyroid tumors including medullary thyroid cancer or multiple endocrine neoplasia syndrome 2 (MEN2)

Because it stays in your system much longer than your natural hormones, it provides a continuous, powerful effect

This can be noticeable as your body adapts to eating fewer calories

Sleep is another critical factor