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(2011, American Journal of Pathology) reported that IGF-1 had plaque-stabilizing effects in a mouse atherosclerosis model useful as a half-life reference (~20-30 hours) and pathway marker

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J Clin Endocrinol Metab (2000) 85(7):240210

Thus, it is imperative that more in vivo studies focusing specifically on atherosclerosis are done to better understand how monocyte and macrophage biology is altered in the setting of G6PD-d

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