D.ColeR
A promising step forward, from reliance solely on venous blood puncture and urine samples, is exploration of the minimal invasive fingertip puncture based dried blood spot (DBS) and dried plasma sport (DPS)

Vitamin B1 (Thiamine) Contributes to: Normal energyyielding metabolism Normal functioning of the nervous system Normal psychological function Normal function of the heart Vitamin B2 (Riboflavin) Contributes to: Normal energyyielding metabolism Maintenance of the normal nervous system function Maintenance of normal skin and mucous membranes Maintenance of normal red blood cells Maintenance of normal skin and mucous membranes Maintenance of normal vision Normal metabolism of iron Protection of DNA, proteins and lipids from oxidative damage Reduction of tiredness and fatigue Vitamin B3 (Nicotinamide) Contributes to: Normal psychological functions Normal energyyielding metabolism Normal function of the nervous system Maintenance of normal skin and mucous membranes Contributes to reduction of tiredness and fatigue Vitamin B6 (Pyridoxine) Contributes to: Normal cysteine synthesis Normal energyyielding metabolism Normal functioning of the nervous system Normal homocysteine metabolism Normal protein and glycogen metabolism Normal psychological function Normal red blood cell formation Normal function of the immune system Reduction of tiredness and fatigue Regulation of hormonal activity Vitamin C (Ascorbic Acid) Contributes to: Maintaining normal function of the immune system during and after intense physical exercise Normal collagen formation for the normal function of: blood vessels, bones, cartilage, gums, skin, and teeth

10.1126/scitranslmed.3010473 Summary Keywords osmolytes, chemical chaperones, TMAO, betaine, choline, cardiovascular disease, liver disease Citation Ilyas A, Wijayasinghe YS, Khan I, El Samaloty NM, Adnan M, Dar TA, Poddar NK, Singh LR, Sharma H and Khan S (2022) Implications of trimethylamine N-oxide (TMAO) and Betaine in Human Health: Beyond Being Osmoprotective Compounds
A case series cannot establish causation, and these patients are not representative of typical incretin users
Glutathione also plays a key role in energy production and methylation, two critical processes at the core of normal cellular function