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However, concerns regarding the safety of such agents, in particular the increased risk of diabetic ketoacidosis (DKA) with SGLT2is, have restricted their widespread adoption in type 1 diabetes [15]

Accompanied by neurologic symptoms such as leg weakness, numbness, bowel or bladder dysfunction, or saddle anesthesiathese are red flags for cauda equina syndrome or severe nerve compression requiring emergency evaluation

The frequency and reporting of these symptoms differ between individual medications within the class, so it's important to consult the specific SmPC for the prescribed product

Ultimately, healthcare providers recognize that optimal GLP-1 timing is a collaborative decision

Always talk to your health care team to figure out what's best for you