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Analyses were performed using JMP v.17.0.0

Metabolic demands are high during wake to support different body movements, food seeking, reproduction as well as survival of the organism from predators (Ding et al., 2018

Conaghan PG

In our study, a J744.A1 mouse macrophage cell line was used to illuminate some mechanisms of interrelationship between hyperuricemia and its possible effect on the expression of oxidative stress-related genes

This can be exemplified by malignant melanoma cells, most often harbouring wild-type p53 (Hussein, 2004), which exhibit overexpression of IGF-1R