The most common adverse effects of tirzepatide are gastrointestinal, including nausea (occurring in 20-30% of patients), diarrhea, vomiting, constipation, and abdominal discomfort
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Ozempic weight loss results Semaglutide (available as Ozempic or Wegovy) leads to significantly greater weight loss: Patients lose an average of 15% of their body weight (over a 68-week trial) Some lose as much as 20% of their body weight About 86% of people taking semaglutide lose at least 5% of their weight, and 50% lose 15% or more For someone starting at 200 pounds, that's about 30-40 pounds lost with semaglutide compared to 10-20 pounds with phentermine
SURMOUNT-2 trial results In Lillys SURMOUNT-2 global phase 3 clinical trial, 938 adult participants with obesity or overweight and type 2 diabetes took weekly treatments of either 15 mg tirzepatide, 10 mg tirzepatide, or placebo for 72 weeks
May also be used around the eye contour
Patient reports suggest that some women do notice alterations in their menstrual patterns whilst taking tirzepatide, but these have not been formally established in clinical studies