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(Initial analysis indicates that body weight reduction with survodutide was driven predominantly by "loss of fat" tissue, with "lean mass" contributing only a small proportion of total weight!) The trial met both weight loss primary endpoints + its key secondary endpoint evaluating waist circumference(a predictor of cardiometabolic risk) together demonstrating survodutide's potential to broadly improve metabolic health

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doi: 10.1111/j.1699-0463.1994.tb04868.x 79 HeathP

PRODUCT BARCODE NO: 608539239191

A randomized Phase I study of the safety, tolerability, pharmacokinetics and pharmacodynamics of BI 456906, a dual glucagon receptor/glucagon-like peptide-1 receptor agonist, in healthy Japanese men with overweight/obesity