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2023;228(1):57.e1-.e18

Both of these injection sites contain major arteries (the jugular and femoral, respectively), and it can be deadly to pierce them by mistake

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Western blot analysis of thoracic aorta proteins showed that the classic aging markers P21 and P16 were significantly downregulated following FOXO4-DRI treatment, whereas the expression levels of the cell proliferation marker Ki-67 and Lamin B, a key protein involved in nuclear structural stability, were markedly upregulated (Figure 1A)

doi: 10.1093/ecco-jcc/jjae145