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10.1016/S0015-0282(00)01630-7 18

Serotonin receptors, particularly the 5-HT2A receptors, have been found to be dysregulated, affecting mood and cognition

Clinical and biological impact of the exposome on the skin

Neither compound has FDA approval or a completed human efficacy trial, so any comparison should be read as mechanism-to-mechanism, not outcome-to-outcome

They are core physiological outcomes with decades of peer-reviewed support behind them

Hemin acts as a potent inductor of HO-1, which promotes the healing process through the reduction of oxidative stress as is evident by the diminished level of lipid peroxidation, and elevated levels of various antioxidant defense mechanisms, including GSH, SOD, GPx, and catalase [55, 120]